Which of the following is a prostaglandin analog used for glaucoma management?

• A. Latanoprost 0.005%
• B. Dorzolamide
• C. Timolol
• D. Acetazolamide

Answer: (A)

Prostaglandin analogs lower intraocular pressure by increasing aqueous humor outflow, mainly through the uveoscleral pathway, via FP receptor activation. Latanoprost 0.005% is a prostaglandin F2α analog and is used as eye drops (often once daily) to reduce IOP. The other drugs listed don’t belong to this class: dorzolamide and acetazolamide are carbonic anhydrase inhibitors (they reduce production of aqueous humor), and timolol is a beta-blocker (also reducing production). So latanoprost is the prostaglandin analog used for glaucoma management.