What is the recommended first action if enrofloxacin retinal toxicity is suspected?

• A. Continue at reduced dose
• B. Stop use immediately
• C. Switch to another antibiotic
• D. Increase frequency

Answer: (B)

When enrofloxacin retinal toxicity is suspected, stopping the drug immediately is essential. Retinal injury from fluoroquinolones can progress quickly and may be irreversible once damage begins, and there’s no antidote to reverse established toxicity. By halting exposure right away, you prevent further harm while you assess the patient and plan alternatives. Continuing at a reduced dose or increasing the frequency would keep exposing the retina to the toxic drug and could worsen injury. Switching to another antibiotic may be needed for ongoing infection, but it doesn’t address the immediate toxicity risk, which is why stopping the drug first is the correct action.