Historic chorioretinitis typically requires treatment:

• A. No
• B. Yes, always
• C. Only if active
• D. Only if vision loss occurs

Answer: (B)

A history of chorioretinitis points to a prior infection where the parasite can remain in the tissue as dormant cysts. Those dormant parasites can reactivate if the immune system becomes weakened, leading to new, potentially vision-threatening inflammation. Because of that risk, treating historic chorioretinitis is commonly done to prevent reactivation and protect vision, especially in scenarios where the patient might become immunosuppressed or during pregnancy planning. Active inflammation clearly requires therapy to control the current infection, but the persistent threat from latent infection means preventive treatment is often warranted even when there’s no current activity.